Role of Calcium Channels in Heavy Metal Toxicity
نویسندگان
چکیده
منابع مشابه
Role of Calcium Channels in Heavy Metal Toxicity
The role of voltage-dependent Ca channels (VDCC) in the membrane permeation of two toxic metals, lead (Pb) and cadmium (Cd), was studied in mammalian cells. Both metals interact with Ca-binding sites, but, while Cd influx appears to occur mainly through the same pathways as Ca, Pb is also rapidly taken up by different passive transport systems. Furthermore, I compared the effect of Cd in two Ch...
متن کاملHeavy Metal Toxicity
Heavy metals are metallic elements which have a high atomic weight and a density much greater (at least 5 times) than water. There are more than 20 heavy metals, but four are of particular concern to human health: lead (Pb), cadmium (Cd), mercury (Hg), and inorganic arsenic (As). According to the U.S. Agency for Toxic Substances and Disease Registry. These four heavy metals are four of the top ...
متن کاملHeavy Metal Toxicity
In general, irritable health concern related to heavy metal (accumulation) might be mainly divided into 2 types, i.e. heavy metal poisoning caused by excessive extrinsic exposure and genetic disorders such as Wilson disease (as reviewed by Osredkar et al. in this issue). As for the former type, unlike the latter one, it can be said that the health damage spread with the development of the civil...
متن کاملProteomics of heavy metal toxicity in plants.
Plants endure a variety of abiotic and biotic stresses, all of which cause major limitations to production. Among abiotic stressors, heavy metal contamination represents a global environmental problem endangering humans, animals, and plants. Exposure to heavy metals has been documented to induce changes in the expression of plant proteins. Proteins are macromolecules directly responsible for mo...
متن کاملHeavy Metal Toxicity and ADHD
Cumulative evidence shows that the long-term prognosis for ADHD is poor, with higher rates of persistent psychiatric problems (Shekim et al., 1990), neurocognitive difficulties (Murphy et al., 2002), and academic struggles (Ratey et al., 1992). Many theoretical models have been put forward to explain the cause of ADHD (Barkley, 1997); however, it is largely recognized that it is a heterogeneous...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: ISRN Toxicology
سال: 2013
ISSN: 2090-6196
DOI: 10.1155/2013/184360